Abstract
In this study, Ag ions in the systems of 60SiO2-(31-x)CaO-4P2O5–5Li2O-(x)Ag2O and 70SiO2-(21-x)CaO-4P2O5–5Li2O-(x)Ag2O (where x = 0, 5, 10 mol %) were substituted for Ca to improve their biological properties. The process of in vitro formation of hydroxyapatite (HA) was investigated through Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES), and its morphology was observed by scanning electron microscope (SEM) and transmission electron microscopy (TEM). According to the results, doping 5 mol % Ag in the both 58S and 68S systems increased the bioactivity. Based on ICP-AES results, the dissolution rates of specimens were inversely proportional to their oxygen density. Furthermore, the viability, the production of ALP enzyme, and bactericidal activity against MRSA bacteria were improved and resulted in significant statistical differences, while bioactive glass with the chemical composition of 60SiO2–26CaO-4P2O5–5Li2O-5Ag2O (58LA05) had the best performance.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
