Abstract
Abstract In this article, by studying some clinical cases of myopia patients and performing the related analyses, we proposed a conjecture for the causes of myopia and its underlying genetic pathway. Based on that, we designed an experiment to prove the hypothesis of individual evolution. Individual evolution refers to the process of individual trait changes caused by certain external environmental factors, which can be inherited to the next generation. The generation (n) of cloned mice will be classified into X (n1, n1…nx) groups, and the daily exercise amount of each group will be defined as Tx (exercise time). Firstly, we will compare the changes in weight and muscle volume among all groups. Subsequently, the first generation of cloned mice will be used to obtain the second generation of cloned mice, and then grouped in the same way. Then, we will evaluate the effects of exercise on gene expression. For the nth generation, the expression levels of individual genes will be determined, and the individual evolution related indexes will be measured. Environmental factors can affect the changes in an individual state, and such alteration can be fed back to the genetic pathways and passed from one generation to the next.
Highlights
The theory of individual evolution is a complement to the principles of biological evolution and the central dogma of genetics
Practical Application: Environmental factors can affect the changes in an individual state, and such alteration can be fed back to the genetic pathways and passed from one generation to the
The bacterial resistance to antibiotics indicates that external environmental factors can alter the expression levels of bacterial related genes, and further to change their phenotypes, which in turn affects the process of population evolution (Malcomson & Mathers, 2017; Kanak & Yilmaz, 2020)
Summary
The theory of individual evolution is a complement to the principles of biological evolution and the central dogma of genetics. Throughout the evolutionary history of higher organisms, when individuals adapt to the changes in their external environment, whether their phenotypic traits could lead to genetic alterations and pass it from one generation to the next? Does an individual evolution occur during the evolutionary history of a species?. Through observing the prevalence of myopia in a selected family, we proposed a conjecture that there are changes in the traits and individuals’ genetic predisposition to myopia, and such defectiveness can be passed to the generation through a genetic pathway (Felberbaum & Küpker, 2015; Abdullah et al, 2020; Altuntas & Korukluoglu, 2019; Kanak & Yilmaz, 2020). We hypothesized the feedback pathway of individual evolution and its underlying genetic mechanisms. We designed an experiment to prove the hypothesis of individual evolution
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