A comparison of vertebral height and bone cement leakage between surgical treatment within 2 weeks and 2 to 4 weeks by kyphoplasty for osteoporotic vertebral compression

Abstract

Objective To compare the vertebral height and bone cement leakage of osteoporotic vertebral compression fracture treated within 2 weeks (time from injury to surgery was less than 14 days) and in 2 to 4 weeks (time from injury to surgery was between 14 and 28 days) by kyphoplasty.Methods Retrospectively analyzed the data of 48 patients with osteoporotic vertebral compression fracture treated by kyphoplasty from January 2010 to January 2011.According to the time from injury to surgery,patients were divided into two groups (surgery within 2 weeks and surgery between 2 and 4 weeks).Twenty-two patients were in surgery within 2 weeks group:4 males and 18 females; aged from 54 to 85 years,with an average age of 71.17 years; fractured segments were distributed between T7 and L4.Twenty-six patients were in surgery between 2 and 4 weeks group:5 males and 21 females; aged from 56 to 88 years,with an average age of 73.12 years; fractured segments were distributed between T7 and L4.Patients' gender,age,bone mineral density,preoperative vertebral body compression rate,intraoperative injection of bone cement volume,postoperative vertebral height restoration rate,1-year follow-up postoperative vertebral height recollapse rate,and bone cement leakage rate were recorded and compared,respectively.Results Preoperative vertebral body compression rate,intraoperative injection of bone cement volume,T-score of BMD,and postoperative vertebral height restoration rate were 47％ ± 21％ and 48％±19％,(3.69±1.03)ml and(3.66±0.71)ml,-2.79±0.57 and-2.87±0.95、25％±8.3％ and 23％±7.7％ in the surgery within 2 weeks group and surgery between 2 and 4 weeks group respectively.There was no significant difference in 4 indicators mentioned above between two groups.The 1-year follow-up postoperative vertebral height recollapse rates were 9％±2.8％ (surgery within 2 weeks) and 11％±2.9％ (surgery between 2 and 4 weeks),respectively.There was significant difference between two groups.Bone cement leakage rates were 22.2％(6/27) in surgery within 2 weeks group and 11.8％ (4/34)in surgery between 2 and 4 weeks group.There was no significant difference between two groups.Conclusion Surgery within 2 weeks and surgery between 2 and 4 weeks can significantly achieve vertebral height restoration,and bone cement leakage rates were similar between two groups,while 1-year follow-up postoperative vertebral height recollapse rate was higher than that in the surgery between 2 and 4 weeks group. Key words: Kyphoplasty; Osteoporotic fractures; Fractures, compression