A COMPARISON OF THE SYMPTOMS, PHYSICAL AND LABORATORY FINDINGS OF MYXEDEMA AND PERNICIOUS ANEMIA; WITH A REPORT OF THREE CASES

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Article1 November 1936A COMPARISON OF THE SYMPTOMS, PHYSICAL AND LABORATORY FINDINGS OF MYXEDEMA AND PERNICIOUS ANEMIA; WITH A REPORT OF THREE CASESJAMES A. GREENE, M.D.JAMES A. GREENE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-10-5-622 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe clinical manifestations of myxedema and pernicious anemia are sufficiently alike to account for the fact that the former disease is frequently mistaken for the latter. The similarities and differences of the two diseases, however, have not been emphasized. The purpose of this report is (1) to compare the clinical manifestations of the two diseases, (2) to present two cases of myxedema in which it was difficult to exclude pernicious anemia, and (3) to report another case of pernicious anemia and myxedema. The data were obtained from the records of 100 unselected cases of pernicious anemia and 33 cases of...Bibliography1. ALT HL: The metabolism in pernicious anemia, Arch. Int. Med., 1929, xliii, 488-503. CrossrefGoogle Scholar2. BALDRIDGEBARER CWA: Studies on the relationship between oxygen consumption and nitrogen metabolism. I. In pernicious anemia, Jr. Clin. Invest., 1931, x, 529-543. CrossrefGoogle Scholar3. CASTLE WB: Observations on the etiologic relationship of achylia gastrica to pernicious anemia. I. The effect of the administration to patients with pernicious anemia of the contents of the normal human stomach recovered after the ingestion of beef muscle, Am. Jr. Med. Sci., 1929, clxxviii, 748-764. CrossrefGoogle Scholar4. STURGISISAACS CCR: Treatment of the anemia of myxedema with liver extract, Proc. Cent. Soc. Clin. Res., Jr. Clin. Invest., 1929-30, viii, 663. Google Scholar5. MEANSLERMANCASTLE JHJWB: The coexistence of myxedema and pernicious anemia, New Eng. Jr. Med., 1931, cciv, 243-248. CrossrefGoogle Scholar6. BALDRIDGEGREENE CWJA: Absence of response of anemia of myxedema to liver extract, Proc. Soc. Exper. Biol. and Med., 1934, xxxi, 1035-1037. CrossrefGoogle Scholar7. LERMANMEANS JJH: Treatment of the anemia of myxedema, Endocrinology, 1932, xvi, 533-540. CrossrefGoogle Scholar8. MUSSIO-FOURNIER JC: Troubles du systeme nerveux dans le myxoedeme, Encephale, 1933, xxviii, 45-62; ibid., 1933, xxviii, 137-159. Google Scholar9. BRIGGS : Cited by Lisser and Anderson.10 Google Scholar10. LISSERANDERSON HEM: Three cases of adult myxedema in women, reported for the purpose of calling attention to their widely different symptomatology and clinical findings, Endocrinology, 1931, xv, 365-381. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Iowa City, Iowa*Received for publication August 10, 1936.From the Department of Internal Medicine, State University of Iowa Medical School. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAssociation of Gastric Carcinoma with Idiopathic Late-Onset Immunoglobulin DeficiencyPAUL E. HERMANS, M.D., F.A.C.P., KENNETH A. HUIZENGA, M.D.Megaloblastic Anemia Secondary to Folate Deficiency Associated with HypothyroidismJOHN D. HINES, M.D., CHARLES H. HALSTED, M.D., ROBERT C. GRIGGS, M.D., JOHN W. HARRIS, M.D.DEFICIENCY OF VITAMIN B12 IN HYPOTHYROIDISMNeurologic Manifestations of MyxedemaCoincidental Myxoedema and Pernicious Anaemia with Subsequent Development of Polycythaemia after Vitamin B12 TherapyVERONICA HALMOS, M.D., F.R.C.P.(C), ROBERT VOLPÉ, M.D., F.R.C.P.(C)Hypothyroidism with anemia demonstrating abnormal vitamin B12 absorption 1 November 1936Volume 10, Issue 5Page: 622-627KeywordsPernicious anemiaResearch laboratories ePublished: 1 December 2008 Issue Published: 1 November 1936 PDF downloadLoading ...