Abstract
The hypotensive effects of the monophosphoric acid ester of thiamine (RO 1–4788) and thiamine hydrochloride were investigated in anesthetized rats and dogs. The depressor effect of thiamine hydrochloride was 40.8% greater than that or RO 1–4788 in the rat and 42.8% greater than RO 1–4788 in the dog.
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