Abstract
Cardiac outputs and arterial pressures were obtained in 9 normal subjects in whom various degrees of tachycardia were induced by atrial pacing before and after the intravenous administration of 2 mg. of atropine. At similar heart rates, atropine produced no change in cardiac index, stroke index, brachial arterial pressure, systolic ejection time, tension time index, total peripheral resistance, mean systolic ejection rate, or left ventricular work index. It is apparent that the effects of atropine on cardiovascular hemodynamics are limited to those related to its chronotropic effect.
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