A comparison of the effect of Fe-3-Specific, versenol, and calcium disodium versenate on urinary iron excretion in a patient with hemochromatosis.

Abstract

Abstract 1.1. A case of hemochromatosis, either idiopathic or secondary to a chronic refractory anemia, is presented in detail. 2.2. Ca EDTA enhanced urinary iron excretion by slightly more than two-fold when given intravenously. 3.3. Versenol, orally given, produced a twofold increase in iron excretion, and, given intravenously, produced more than a fourfold increase. 4.4. Fe-3-Specific by mouth had little effect and intravenously approximately doubled urinary iron excretion. 5.5. Phlebotomy was the treatment of choice in this patient, in spite of a pre-existing, mild, hypochromic, microcytic anemia.