Abstract
4 geographical strains of Schistosoma mansoni, Puerto Rican, Brazilian, Egyptian and Tanzanian, each maintained in its local snail host, were studied in mice. On exposure to a given number of cercariae the animals infected with the Puerto Rican strain developed the largest number of worms, followed by the Egyptian strain and then by the Tanzanian and Brazilian strains. The production of liver disease was studied in mice each harbouring only one pair of worms. The Brazilian and Puerto Rican strains appeared to be most virulent in this regard, the Egyptian strain causing the least severe liver reaction and the Tanzanian strain producing the fewest eggs.
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