Abstract
The nucleotide fragments arising from digestion of Aspergillus nidulans mitochondrial and cytoplasmic ribosomal RNAs with T1 ribonuclease have been compared by means of two dimensional ionophoresis. Major qualitative and quantitative differences were found to exist between the two ribosomal RNA species. In addition, distinct differences were observed between the fingerprint patterns of the heavy and light components within each ribosomal RNA sample. The larger component of mitochondrial ribosomal RNA presented a more complex ionophoretic pattern than the smaller one, implying that the former was not a simple dimer of the latter.It is concluded that the nucleotide sequence of the mitochondrial rRNA differs from that of the homologous cytoplasmic rRNA species.
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