Abstract

Objective: To compare the efficacy of intralesional triamcinolone acetonide with surgical incision and curettage in patients with chalazion. Material and Method: This longitudinal interventional study was carried out during 1st September 2015 to 31st August 2016 at Kamlesh Netralaya Hospital at Ambikapur, Chhattisgarh in central India. Total 60 patients with Chalazion of (≥2mm in size) were randomly divided into two groups of 30 patients each. The first group of patients (N=30) was treated by 0.1 to 0.2 mL intralesional triamcinolone acetonide injection (40 mg/mL) and the second group of patients (N=30) were treated surgically by incision-curettage. Post steroid injection, the reduction in chalazion size was measured at 2 weeks and at 4 weeks. Results: Out of 60 patients, 58.33% were females with mean age of 31.8 ± 9.1 years. There were total 79 chalazion in two groups. Among those treated using intralesional triamcinolone acetonide (ILTA), 29 (70.73%) chalazion resolved at 2 week. The unresolved chalazion were repeated the ILTA injection at 2nd week and followed till 4 week. The mean 11-point numerical rating scale (NRS) score for pain intensity was significantly lower in ILTA group as compared to IC group (2.3± 0.42 vs 6.7 ± 1.2, P-value = 0.001). Conclusion: The results of intralesional triamcinolone acetonide injection treatment are comparable to that of surgical incision and curettage (IC) after second injection. Patients experienced less pain and were more satisfied with the intralesional triamcinolone acetonide injection.

Highlights

  • Localized cyst on eyelids consisting of lipogranulomatous inflammation is called as Chalazion [1]

  • intralesional triamcinolone acetonide (ILTA) was significantly associated with lesser pain and better patients satisfaction in chalazion treatment as compared to incision and curettage

  • Complete healing with less anxiety and discomforts to patients are the advantages of intralesional triamcinolone acetonide over surgical procedure for primary and recurrent chalazion treatment

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Summary

Introduction

Localized cyst on eyelids consisting of lipogranulomatous inflammation is called as Chalazion [1]. Individuals of all ages can be affected, but more frequently it appears in adults It can present as uniform or multiple, as well as recurrent. Intralesional steroid injection for chalazion has been reported to be effective with high success rates [7,8,9,10,11,12,13,14]. This treatment modality is useful in children and in patients where cooperation for incision and curettage is difficult. The present study was conducted with the objective of to compare the efficacy of applied therapy in two groups of patients with chalazion, one undergoing incision and curettage and the other giving intralesional triamcinolone acetonide on chalazion

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