Abstract
The distribution of the different free amino acids in plasma and in two aortic wall layers are compared. The following findings are presented: There is a higher concentration of free amino acids in the arterial wall than in the plasma. For the major part of the essential amino acids, one finds 1.5 to 3 times more in the aortic wall. For some others, especially for the amino acids synthetized by the Krebs pathway, the difference is much more important. Several amino acids present in the aortic wall could not be detected in the plasma. These findings suggest an active transport of amino acids against a concentration gradient and the synthesis of some other amino acids in situ.
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