Abstract
The relative effect of acid lead arsenate and sodium fluosilicate on the silkworm was studied by three laboratory methods, namely, the sandwich method for the estimation of the median lethal dose, the sandwich method for the determination of the relation between dosage and speed of toxic action, and the simple cage test. The relative effect of the same compounds on mosquito larvae, Culex pipiens L.,was studied by the method of Marcovitch. It was concluded that only the first two of the foregoing methods measure the relative toxicity of stomach-poison insecticides and that the first of the two is the more practicable for the purpose. The last two methods may be suitable for measuring the relative effectiveness of stomach poisons. The cage test with appropriate insects should usually be the better of the two for this purpose. The toxicity of sodium fluosilicate to the fourth-instar silkworm ranges from one to two times that of acid lead arsenate, depending on the method and criterion employed for its estimation. Any dose of the fluosilicate affected the silkworm more rapidly than the same dose of the arsenate.
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