Abstract
SUMMARY Sheep were infected with Corynebacterium ovis and observations made on the value of five serological tests in detecting infected animals. It was found that no single test correctly identified all the infected sheep. Tube agglutination (TA) test was of value between three and 18 weeks after infection. Antibodies were not detected by the complement fixation (CF) test after the eighth week of infection and non-specific reactions occurred with the gel-diffusion (GD) test. The anti-haemolysin inhibition (AHI) test failed to detect antitoxin in a high proportion of infected sheep which were positive for C. ovis on culture. The indirect haemagglutination (IHA) test was more reliable and diagnostic levels of antitoxin persisted for longer periods than antibodies to the other tests. Therefore, it was concluded that the IHA test had an advantage over the other tests for the serological diagnosis of C. ovis infection in sheep.
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