A Comparison of Fine Needle Aspiration Cytology (FNAC) with Tru-cut Biopsy in Breast Lump Patients Taking Histopathology as Gold Standard

Abstract

Objective: To compare sensitivity and specificity of FNAC with Tru-cut biopsy diagnosis of breast lump patients. Material and Methods: It was a cross sectional study conducted at surgical department of Gulab Devi Teaching Hospital Lahore from January 2022 to December 2022. Atotal of 122 patients presented in surgical OPD with complaints of breast lump of size between 2cm to 4 cm were included in the study with their consent. All these patients underwent FNAC, true cut biopsy and excisional biopsy. Sensitivity and specificity of both FNAC and true cut were calculated. Results: Mean age of patients included in this study was 35.4 ± 14.6 years. The sensitivity and specificity of FNAC in benign breast diseases was 98.2% and 74.2% respectively while in malignant diseases it was 72.7% and 98.8% respectively (p-value 0.00). The sensitivity and specificity of Tru-cut in breast diseases was 100% and 97.1% respectively while in malignant diseases it was 97% and 98.2% respectively (p-value 0.00). Conclusion: Breast lump is more common in females as compared to males. Breast carcinoma is more common in old females and benign breast diseases is common among young females. Tru-cut biopsy is better than FNAC in diagnosis of both benign and malignant lesions of breast lumps.