Abstract
ObjectiveThe purpose of this study was comparing the erythrocyte sedimentation rate (ESR) results of trisodium citrate (TSC) and ethylene diamine tetra-acetic acid (EDTA) anticoagulants. A comparative cross-sectional study was conducted at the University of Gondar specialized referral hospital, northwest Ethiopia. A total of 70 TB presumptive participants were recruited. From each of the 70 participants of the study, 3 and 1.6 ml of blood was collected in EDTA tubes and 0.4 ml of trisodium Citrate anticoagulant containing test tubes, respectively.ResultsThe mean ± SD values of ESR were 57.9 ± 41.45 mm/h in EDTA and 50.99 ± 43.5 mm/h in TSC anticoagulated blood. The mean difference of ESR values between EDTA and TSC blood (6.91 ± 13.66 mm/h) was statistically significant. The Mean ± SD of ESR values using EDTA and TSC in males were 59.57 ± 42.31 and 53.57 ± 44.61 mm/h while for females it was 54.71 ± 40.44 and 46.04 ± 41.82 mm/h, respectively. The study indicated that there was a significant difference between ESR values with EDTA and TSC anticoagulants.
Highlights
Erythrocyte sedimentation rate (ESR) is a common inexpensive, sensitive and non-specific hematology test frequently ordered in clinical medicine
The study indicated that there was a significant difference between ESR values with ethylene diamine tetra-acetic acid (EDTA) and trisodium citrate (TSC) anticoagulants
Comparison of ESR values The Mean ± standard deviation (SD) ESR values of patients according to EDTA and TSC anticoagulated blood were 57.9 ± 41.45 and 50.99 ± 43.5 mm/h, respectively
Summary
Erythrocyte sedimentation rate (ESR) is a common inexpensive, sensitive and non-specific hematology test frequently ordered in clinical medicine. It is the most widely used laboratory test for evaluating and monitoring the Increased amounts of the plasma proteins, like fibrinogen are the major factors which increase ESR test results by reducing the negative electrostatic force among red blood cells (RBCs), leading to an increased rate of rouleaux formation and the easy falling down of RBCs within plasma [7, 8]. Increased ESR can be used as an inexpensive “sickness index” in the elderly [22]
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