Abstract
A comparison was made of the composition of fragments isolated from ribonuclease digests of RNA from liver tissue of normal and whole-body x-irradiated rats. Four hours after the end of irradiation the content of RNA was found to decrease up to 30% when compared with that of normal animals; at the same time the basic analytical characteristics remain essentially the same (the content of phosphorus, nitrogen, DNA, proteins, and amino acids, and the nucleotide composition and the absorption spectra). The qualitative composition of the enzymic digests is also identical. Marked differences between the two RNA's were found to lie in the amounts of some fractions (C, U, AAC, (GGA) U). Larger amounts of the latter were always contained in the hydrolyzate of RNA from the tissue of irradiated animals. In conclusion, the determined differences pertaining to the quantitative pattern of several fragments were discussed from the aspect of possible irradiation-induced changes in the inner arrangement of the polynucleotide chain of RNA.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
