Abstract
Screening programmes for inapparent congenital rubella infection have created a need for accurate methods of laboratory diagnosis of this disease in the newborn. Demonstration of rubella-specific immunoglobulin M (IgM) antibody in either cord blood or neonatal serum is accepted as the most convenient method available. This study reports a chromatographic method with Controlled Pore Glass for demonstrating rubella-specific IgM antibody. The technique is more practical for use in the diagnostic laboratory than other currently advocated methods of serum separation and is at least as sensitive.
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