Abstract

Review question / Objective: The aim of our study is to investigate the impact of various types of adductor and femoral nerve blocks on clinically relevant outcomes in patients following elective primary total knee arthroplasty (TKA). (i) population: adults undergoing primary TKA with general or neuraxial anesthesia receiving any of the analgesic techniques below. (ii) intervention/comparator: single-shot or continuous adductor canal/femoral nerve block. (iii) outcomes: VAS/NRS pain score at rest and mobilization at 24 and 48 h; amount of opioid consumption at 24h and reported consumption; quadriceps muscle strength at 6-8 and 24h; timed up and go (TUG) test at 24 and 48h; degrees of maximum flexion (range of motion); length of hospital stay and nausea/vomiting. (iv) study design: randomized controlled trials (RCT); retrospective cohort studies.

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