Abstract

Attention Deficit and Hyperactivity Disorder (ADHD) comprises a disorder which is charac‐ terized with inattention, hyperactivity and impulsivity, seen in 3-7% of school-age children Boys are two to nine times more often affected than girls [1]. Twin, adoption, and molecular genetic studies show ADHD to be highly heritable. Evidence from animal and human studies implicates the dysregulation of frontal-subcortical-cerebellar catecholaminergic circuits in the pathophysiology of ADHD. Imaging studies suggest that abnormalities of the dopaminergic and adrenergic transmitter systems lead to impaired neurotransmission [2]

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