A COMPARATIVE STUDY TO EVALUATE THE EFFICACY OF CARBOXYMETHYLCELLULOSE AND POLYETHYLENE GLYCOL ARTIFICIAL TEARS ON SUBJECTIVE AND OBJECTIVE PARAMETERS OF DRY EYE DISEASE

Abstract

Purpose: To compare the changes in Ocular Surface Disease Index (OSDI) and Tear Film Break up Time (TBUT) with carboxymethylcellulose and polyethylene glycol containing articial tears in patients of dry eye disease (DED). Methods: This prospective randomized study consisted of patients above 18 years of age diagnosed as a case of dry eye disease. The patients were equally divided into two groups; Group A & Group B. Participants in Group A were prescribed carboxymethylcellulose (0.5%) containing articial tears while participants in Group B were prescribed polyethylene glycol (0.4%) containing articial tears. OSDI and TBUT scores were recorded at baseline, at 1 week and then at 6 weeks. Results: OSDI and TBUT scores were comparable at baseline in both the groups. Group B had signicantly improved OSDI and TBUT scores compared to Group A after 1 week and also after 6 weeks. Conclusion: Polyethylene glycol (0.4%) articial tears are superior to Carboxymethylcellulose (0.5%) articial tears in improving OSDI as well as TBUT scores in DED patients