Abstract
Objective:The main objective of this study is to find out the effectiveness and efficacy of topical 1.5% Acetic acid (antiseptics) in comparison to topical 0.3% Gentamicin sulphate in case of chronic suppurative otitis media (CSOM) patients. Material and Methods: After the written informed consent, detailed history and otoscopy of CSOM patients, fulfilling the inclusion and exclusion criteria was selected. A total 88 patients were diagnosed as CSOM (safe type) patients in OPD of ENT, in Teerthanker Mahaveer Medical College and Research Centre, TMU, Moradabad, UP. India, with age 15 to 60 years in both sexes, were randomly divided in to two groups, group A (n=44) for topical 1.5% Acetic acid and group B (n=44) for topical 0.3% Gentamicin sulphate as control.Treatment succeeded was based on changes in the otological symptoms scores at day 14 visit. It was subdivided into two categories: (a) “clinical cure” if the otological symptom score was 5otological symptoms score on day 14. Observation and Result:In the present study it has been shown that both acetic acid and Gentamicin sulphate were statistically equally effective in the treatment of CSOM. The effectiveness difference for otological symptom score between two drugs narrowed after one week of treatment, but both remained statistically significant till the end of treatment duration (p-value < 0.05). But the response with acetic acid was somewhat earlier and complete as compared to Gentamicin sulphategroup. Conclusion:Topical 1.5% Acetic acid solution is clinically effective and better option than topical 0.3% Gentamicin sulphate in the treatment of active tubotympanic type of chronic suppurative otitis media because of emergence of antibiotic resistance and cost effective treatment in otorrhoea. Keyword:CSOM, Topical Acetic acid, Topical Gentamicin, Effectiveness, Efficacy.
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