A Comparative Study on Applications of Novel Drug Delivery System for Herbal Formulations

Abstract

For plant actives and extracts, novel drug delivery systems (NDDS) have made great strides in the past few years. Bioactive and plant extracts have been used to create a variety of novel herbal formulations, including polymeric nanoparticles, nanocapsules, liposomes, phytosomes, nanoemulsions, microspheres, transferosomes, and ethosomes. There are a number of advantages that the novel formulations have over conventional formulations, including improved solubility, bioavailability, protection from toxicity, enhancement of pharmacological activity, improved tissue distribution of macrophages, sustained delivery, and protection from physical or chemical degradation, among others. A review of the current state of herbal formulation development, including preparation method, active ingredient type, size, entrapment efficiency, route of administration and biological activity is highlighted in the present work.