Abstract
The incidences of inammatory diseases are increasing in Asia with maximum incidence in India among the south-east Asian countries. There is a need for development of novel approaches to treat or prevent the diseases using eco-compatible drugs. Paan or Piper betle has been traditionally known as a recreational food. However due to its properties it is a functional food as well. Ayurveda illustrates the use of Paan as a nutraceutical. Paan is known to possess antioxidant, anti-inammatory, anti-apoptotic, anti-cancer and anti-microbial properties. The essential oil (1%–3%) in leaves are used in making ayurvedic medicines and herbal products. Exploration of its anti-oxidative potential may reveal some bioactive or higher phenolic and avonoid compound to enhance its nutritive value and help in combating various inammatory and degenerative diseases. With this aim, we have planned to screen a number of varieties of paan collected from different districts of West Bengal, by a panel of different cell free antioxidative biochemical assays, to compare four different anti-oxidative potentials in four different cultivars of a particular geographical location and in a particular season (summer) of collection from Howrah district of West Bengal. The study revealed the best variety of Howrah district which has the potential to combat the inammatory and degenerative diseases
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