A Comparative Study of the Use of Whole Liver, Liver Extract and Ventriculin

Abstract

Article1 May 1932A Comparative Study of the Use of Whole Liver, Liver Extract and VentriculinHUGO A. FREUND, A.B., M.D., F.A.C.P., ALVIN E. PRICE, A.B., M.D.HUGO A. FREUND, A.B., M.D., F.A.C.P.Search for more papers by this author, ALVIN E. PRICE, A.B., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-5-11-1377 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe use of various anti-anemic substances in the treatment of primary anemia is now well recognized and established in medical therapeutics. Although sporadic cases have appeared in the literature in which some form of liver therapy has failed, there is abundant evidence which demonstrates the undoubted value of anti-anemic substances. As to their comparative value, however, there is relatively little to be found which indicates any difference in response to them. Thus, Minot and his co-workers1report that they noted no difference in the reticulocyte response obtained in the feeding of either whole liver or liver extract. Ordway and Gorham2...References1 MINOTMURPHYSTETSON GWR: The response of the reticulocytes to liver therapy; particularly in pernicious anemia, Am. Jr. Med. Sci., 1928, clxxv, 581-599. CrossrefGoogle Scholar2 ORDWAYGORHAM TLW: The treatment of pernicious anemia with liver and liver extract, Jr. Am. Med. Assoc., 1928, xci, 925-928. CrossrefGoogle Scholar3 DAVIDSONMCCRIEGULLAND SJGGL: The treatment of pernicious anemia with liver and liver extracts, Lancet, 1928, i, 847-852. CrossrefGoogle Scholar4 ISAACSSTURGIS RC: Some newer remedies in the treatment of pernicious anemia—desiccated stomach, Jr. Am. Med. Assoc., 1930, xcv, 585-587. CrossrefGoogle Scholar5 CONNER HM: The treatment of pernicious anemia with swine stomach, Jr. Am. Med. Assoc., 1930, xciv, 388-390. CrossrefGoogle Scholar6 SCHULTEN H: Über Misserfolge der Lebertherapie der perniziösen Anämie und ihre Ursachen, Münch. med. Wchnschr., 1930, lxxvii, 59-61. Google Scholar7 BERGLUNDWATKINSJOHNSON HCR: Significant difference in response of pernicious anemia to fetal calf and beef liver feeding, Proc. Soc. Exper. Biol. and Med., 1928, xxv, 834-835. CrossrefGoogle Scholar8 ISAACS R: Systemic relapses during liver induced hemopoietic remissions in pernicious anemia, Am. Jr. Med. Sci., 1929, clxxviii, 500-505. CrossrefGoogle Scholar9 SMITHBURNZERFOS KCLG: The inhibitory action of infection and fever on the hematopoietic response in a case of pernicious anemia, Ann. Int. Med., 1931, iv, 1108-1111. Google Scholar10 MEULENGRACHTHOLM ES: Eosinophilia in liver diet, Am. Jr. Med. Sci., 1930, clxxix, 199-208. CrossrefGoogle Scholar11 MINOT GR: The treatment of pernicious anemia with liver or an effective fraction of liver, Tr. Coll. Phys., 1927, xlix, 144-153. Google Scholar12 BERGLUND H: Liver diet in pernicious anemia, Ann. Int. Med., 1928, ii, 471-473. Google Scholar13 GOLDHAMER SM: Non-development of eosinophilia in pernicious anemia patients treated with desiccated stomach, Ann. Int. Med., 1931, iv, 1105-1107. Google Scholar14 ISAACSSTURGISSMITH RCM: Treatment of pernicious anemia, Jr. Am. Med. Assoc., 1928, xci, 1687-1690. CrossrefGoogle Scholar15 MINOTCOHNMURPHYLAWSON GREJWPHA: Treatment of pernicious anemia with liver extract; effects upon the production of immature and mature red blood cells, Am. Jr. Med. Sci., 1928, clxxv, 312-317. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Detroit, Michigan*From Department of Internal Medicine, Harper Hospital, Detroit, Mich.†Received for publication, September 17, 1931. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1932Volume 5, Issue 11Page: 1377-1383KeywordsAnemiaHospital medicineLiverReticulocytes Issue Published: 1 May 1932 PDF downloadLoading ...