Abstract
X-Ray-induced chromosomal aberrations (CA) were potentiated by post-treatments in G 2 with either caffeine (caff) or poly- d-lysine (PDL) in root-tip cells of Allium cepa. The enhancement of the yield of CA was concomitant with an increase in the frequency of mitosis. Our results seem to support the idea of a direct relationship between radiation-induced G 2 delay and repair of chromosome damage. Here we report on similarities between caffeine and PDL in both decreasing G 2 delay and enhancing chromatid aberration yield. The possible molecular mechanism(s) of action responsible for the cytogenetic effects observed are discussed.
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Schedule a callMore From: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
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