A Comparative Study of the Levels of Heat Shock Protein 70, Some Biochemical and Hormonal in the Blood of Cows Suffering from Follicular Cystic Ovarian and Endometritis

Abstract

Twenty- four reproductive systems of Frisian cross breed cows, aged between (3-5years) were obtained from Basrah abattoir during the period of (2nd March 2020 - 30th June, 2020). They were divided into 3 groups of cows with ovarian follicular cystic (n=8), cows with endometritis (n = 8), and healthy cows (n=8) depending on clinical signs. The main gall of this paper compare and report the different values of heat shock protein 70 (HSP70), some biochemical and hormonal levels in those cows in the native Basrah climate. Samples of blood were collected from all cows subjected to this study and serum was harvested from each individual sample by centrifugation. Heat shock protein 70 (Hsp70), total protein (TP), albumin(Alb), globulin, total cholesterol (Cho), triglyceride (TG), low density lipo-protein(LDL), aspartate aminotransferase (AST), cortisol, testosterone, thyroid stimulation hormone (TSH), thyroxin (T4) and triiodothyronine hormones(T3) were measured in serum samples. Results revealed a significant increase (p≤0.05) in the level of Hsp70, and thyroid stimulation hormones (TSH) of cows with two pathological cases (endometritis and follicular cysts) compared with those healthy cow. Significant decrease (p≤0.05) in the measurement of total protein, albumin, globulin, thyroxin (T4), triiodothyronine (T3) hormones, cholesterol, triglyceride, and low density lipoprotein (LDL) in cows having those two genital diseases compared with normal cows. The results also were revealed a significant increase (p≤0.05) in the level of testosterone hormone in cows with follicular cystic ovarian case compared with endometritis case and control ones. Finally, significant increase (p≤0.05) in cortisol hormone level and aspartate aminotransferase (AST) activity in cows with endometritis case compared with the control one and follicular cystic ovarian cases.