Abstract

1. 1. The ability of muscle and nervous tissue from mice, mussels, crabs, snails and cockroaches to metabolise U- 14C glutamic acid was compared. 2. 2. A number of differences in the relative distribution of the radiocarbon among the soluble intermediates (aspartic acid, alanine, glutamine, malic acid, succinic acid, citric acid, fumaric acid, α-oxoglutaric acid) was observed although in general the actual qualitative pattern was similar in the species tested. 3. 3. Exceptions to this were the significant formation of γ-aminobutyric acid in the mouse and cockroach and the high proportion of glutamate carbon converted by the crab to an unknown compound designated U8. 4. 4. No specific pattern of glutamate metabolism emerged for nervous tissue as distinct from muscle.

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