Abstract
An apparatus has been designed and an in vitro method employing radioisotopes has been developed to study medicament release from pharmaceutical semisolids. Radio-labeled mercuric and iodide ions have been incorporated into hydrophilic bases emulsified with 1, 3, and 5 per cent concentrations of anionic, cationic, and nonionic surface active agents and the ability of the bases to release the contained ions has been measured.
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