Abstract
Objective To compare the value of power doppler imaging (PDI) , advanced dynamic flow (ADF) and superb microvascular imaging (SMI) in evaluation of disease activity of Crohn′s disease (CD) . Methods A total of 40 CD patients were recruited in this retrospective study. All the inflamed bowels were examined and graded by gray scale ultrasound, PDI, ADF and SMI. The physician′s diagnosis was set as the standard to differentiate disease activity. The results observed respectively by senior and junior doctor were compared for consistency. Results PDI, ADF and SMI evaluated the disease activity with sensitivity of 60.0%, 60.0% and 90.0%, specificity of 80.0%, 90.0% and 80.0%, and diagnostic accuracy of 65.0%, 67.5% and 87.8%, respectively. SMI was more sensitive and accurate to evaluate disease activity of CD compared with PDI and ADF. The result observed by junior doctor was consistent with that by senior doctor (Kappa value: 0.907, 0.755 and 0.720, P<0.001) . Conclusion SMI can evaluate the disease activity of CD with higher sensitivity and accuracy in comparison with traditional PDI and ADF. Key words: Crohn′s disease; Disease activity; Doppler ultrasonography
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