Abstract
1. 1. The metabolism acid has been studied in marine and terrestrial species from the Phylum Annelida with 14C substrates. 2. 2. Radioactive 3-β-hydroxy sterols were isolated from all polychaetes injected with 2- 14C mevalonic acid; one of the labeled sterols found in Nereis diversicolor has been isolated and identified as cholesterol. 3. 3. In contrast, no 14C-3-β-hydroxy sterols were detected in the terrestrial species, Lumbricus terrestris, but a large amount of radioactivity was found in squalene; this species can synthesize squalene, but is unable to cyclize this intermediate to digitonin-precipitable sterols. 4. 4. Similar results were obtained both in the presence and absence of antibiotics.
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