Abstract

I. Introduction The prognosis of patients with acute myocardial infarction (AMI) is directly related to left ventricular (LV) function and size 1.2 Traditionally, the principal investigated target of clinicians is LV function, with little interest in the right ventricle.However, right ventricular (RV) dysfunction after AMI is also associated with increased risk of morbidity and mortality. 3-5 RV dysfunction has been associated with increased morbidity and mortality in patients with congenital heart disease, valvular disease, coronary artery disease, pulmonary hypertension, and heart failure. 6-8 Right Ventricle (RV) dysfunction may be primarily attributed to abnormality of RV myocardium or secondary to left ventricle (LV) dysfunction, as a consequence of Ventricular Interdependence between the two ventricles, as they are encircled by common muscle fibres, share a common septal wall and are enclosed within a common pericardium. 9 Early recognization of RV dysfunction is warranted but till today it remains a challenging task because of complex structure and asymmetric shape of RV. 10 Most of the previous studies have evaluated RV functions in patients of inferior myocardial infarction. There are only few studies available in literature evaluating RV function in anterior myocardial infarction. Therefore, in the present study conventional echocardiography combined with tricuspid annular plane systolic excursion [TAPSE Fractional area change(FAC), pulsed doppler and TDI were used to evaluate the effect of different infarction sites on RV functional changes in patients with first acute ST-elevation myocardial infarction (STEMI) without concomitant RV infarction.

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