A comparative study of “Idiopathic catatonia” with catatonia in schizophrenia

Abstract

Catatonia has been defined as a cluster of signs and occurs secondary to or as a subgroup of schizophrenia, mood disorders or organic syndrome. This study specifically examined the distinct variety of catatonia that did not meet any standard psychiatric diagnostic criteria on globally recognised psychiatric rating tools and compared the clinical features with the catatonia that occurred in association with a diagnosis of schizophrenia. The inpatients in a tertiary psychiatric ward in Ahmedabad, India, between 2002 and 2005 who presented with two or more catatonic signs present for more than 24 h period were assessed on Structured Clinical Interview for DSM IV tool. Those with catatonic signs that met diagnostic criteria for schizophrenia ( n = 21) were compared, with those without any disorder called Idiopathic catatonia ( n = 13), on measures of Bush Francis Catatonia Rating Scale (BFRCS), Brief Psychiatric Rating Scale (BPRS) and Scale for Assessment of Negative Symptoms (SANS). The scores on duration of illness ( U = 14.00; p < 0.001) and mean BPRS ( t = 6.76; df = 32; p < 0.001) were significantly higher in schizophrenia group. The Idiopathic group had significantly higher scores on mean total BFCRS ( t = −3.50; df = 32; p = 0.001) and also on subscores of negativism ( p = 0.02), waxy flexibility ( p = 0.02), mitgehen ( p < 0.05) and ambitendency ( p = 0.01). The results indicate that the Idiopathic catatonia present early in their course and have fewer general psychopathologies; however have higher number and severity of catatonic signs. The study also supports the current concept that there does exists, a distinct variety of catatonia that probably has its own course and prognosis, which need further consideration and more studies to explore this.