Abstract
Background The human skeleton is the most common organ to be affected by metastatic cancer (skeletal or bone metastases). The prevalence of skeletal disease is greatest in breast and prostate carcinoma. Bone metastases lesions weaken bone structure, causing a range of symptoms and complications. Sufferers of breast and prostate cancers may develop Skeletal related events (SRE). These SRE are defined as pain that require palliative radiotherapy or surgery to bone, hypercalcaemia, pathologic fractures, spinal cord compression and bone marrow failure. These complications contribute to a decline in patients’ HRQOL (health related quality of life). However, information on treatment costs of breast and prostate cancers and multidimensional assessments of QOL are limited. Thus this study aim to obtain both cost and QOL of breast and prostate cancers patients and to determine their relationship with the patients sociodemograhic profiles (age, ethnicity, income) and disease profile (tumour types, cancer stages and SRE status).
Highlights
The human skeleton is the most common organ to be affected by metastatic cancer
The prevalence of skeletal disease is greatest in breast and prostate carcinoma
The association of risk factors and cost and QOL will later be determined through statistical analysis
Summary
The human skeleton is the most common organ to be affected by metastatic cancer (skeletal or bone metastases). Sufferers of breast and prostate cancers may develop Skeletal related events (SRE). These SRE are defined as pain that require palliative radiotherapy or surgery to bone, hypercalcaemia, pathologic fractures, spinal cord compression and bone marrow failure. These complications contribute to a decline in patients’ HRQOL (health related quality of life). This study aim to obtain both cost and QOL of breast and prostate cancers patients and to determine their relationship with the patients sociodemograhic profiles (age, ethnicity, income) and disease profile (tumour types, cancer stages and SRE status)
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