A comparative study of awakening characteristics after propofol based total intravenous anaesthesia and sevoflurane based volatile induction and maintenance anaesthesia in short surgical procedure

Abstract

To maintain hemodynamic parameters and rapid emergence is a challenge for anaesthesiologist in emerging era of early recovery. The aim of this study was to assess recovery characteristics of propofol and sevoflurane for induction as well as maintenance of anaesthesia in short surgical procedures. Sixty patients were assigned randomly into two groups. Group P patients were induced with 2mg/kg propofol intravenously followed by infusion of 12mg/kg/hr for 10mins, 10mg/kg/hr for 20 mins and 8mg/kg/hr till end of procedure. Group S patients were induced with 8% sevoflurane in 4L/min nitrous oxide and 2L/min oxygen mixture and maintained with 3.5% sevoflurane with spontaneous breathing. LMA was inserted in all patients. LMA insertion time and insertion attempt were observed. Time from end of procedure to first spontaneous movement, spontaneous eye opening, removal of LMA, followed verbal commands and became fully oriented to time and place, time to achieve Aldrete score ≥9 (phase I recovery) and time to achieve PADSS score ≥9(phase II recovery) were noted. Phase 1 recovery time was less in sevoflurane group as compared to propofol group. Phase 2 recovery time was less in propofol group as compared to sevoflurane group. They were statistically significant. Incidence of both nausea and vomiting was significantly higher in the sevoflurane group. We concluded that sevoflurane provides rapid induction with LMA insertion condition comparable with propofol. Sevoflurane provides early phase I recovery where as home readiness is early with propofol. Sevoflurane can be a suitable alternative to propofol for induction and maintenance.