Abstract
AbstractA fluidised bed reactor with liquid recycle (FBR) and an external loop gas lift reactor (GLR) were designed for the production of isopropanol—butanol mixtures by immobilised Clostridium spp. and scaled down to laboratory scale (part I). Hydrodynamic models were set up for the two laboratory scale reactors. Liquid mixing in the 10 dm3 FBR was described by 10 tanks in series. Fluidisation velocities, bed expansions and axial dispersion coefficients agreed well with literature data. Liquid mixing in the 15 dm3 GLR was described by 100 tanks in series. The gas hold‐up and circulation velocity were found to decrease with increasing hold‐up of solids, in accordance with literature indications. No influence of the hold‐up of solids on the axial dispersion coefficient was determined. An integrated reactor model was set up for both reactors, using the hydrodynamic and kinetic model. Actual fermentation data are presented and compared with model predictions in part III of this study; this part will also include a comparison of reactor performances and scale up aspects.
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