A comparative study for the efficacy of different forms of ozone as a treatment for alveolar osteitis

Abstract

AbstractPurposeDry socket is one of the most common complications following dental extraction. Although blood clot disintegration is known to be the cause of the condition, an agreement is lacking regarding the relative merits of various treatment methods. Despite the fact that ozone is one recommended therapy, the literature is deprived of any comparative study for the different forms of ozone delivery. The aim of the current study therefore was to evaluate the efficacy of different forms of ozone as a treatment for this condition.MethodsA total of 1521 patients were categorized into four groups (I, II, III and IV) according to pain severity depending on the need and the response to analgesics (mild, moderate, severe or agonizing, respectively). Each group was randomly and blindly divided into three subgroups according treatment method: Oleozon (Ole) which is an ozonized olive oil, ozonized water (OW), ozone gas (O3).ResultsWhile Ole, OW and O3 were curative in groups I and II, only O3 was curative for groups III and IV. OW was palliative in group IV. Only O3 was definitive therapy for all groups.ConclusionOzone in the gaseous form is the most potent form of ozone therapy. Although ozonized oil shows the weakest form, OW had an intermediate potency.