Abstract
Pituitary-dependent hyperadrenocorticism (PDH) is frequent in dogs. Little is known about its presentation in different age groups and its characteristics. Dividing the population under study ( n = 107) into three age groups we observed that 11.2% were young, 51.4% adults and 37.4% aged. Using magnetic resonance, pituitary tumours were intra-sellar (IS) in 30.8% and extra-sellar (ES) in 62.6% and the pars intermedia (PI) was affected in 6.5%. ES are predominant in females and IS in males ( p < 0.0001). In the adult-aged population, the ES and PI are predominant, while in the young, the IS predominate ( p < 0.0001). ACTH concentration was greater in the ES vs. IS ( p < 0.05). α-MSH did not present significant differences according to tumour size, showing a negative correlation ( r = −0.47; p < 0.01) vs. ACTH. Differences in adenoma size according to gender and their age-related frequency of apparition could be because of different origins of the corticotrophinoma.
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