Abstract

A comparative study between the efficacy of 35% glycolic acid peel and triple combination cream in the treatment of melasma - IJCED- Print ISSN No: - 2581-4710 Online ISSN No:- 2581-4729 Article DOI No:- 10.18231/2581-4729.2018.0029, IP Indian Journal of Clinical and Experimental Dermatology-IP Indian J Clin Exp Dermat

Highlights

  • Melasma is an acquired symmetric hypermelanosis characterized by irregular light to greyish brown macules on sun exposed skin, usually face

  • A total number of 60 patients with facial melasma attending the outpatient Department of Dermatology, Venereology and Leprosy of our Medical college and Hospital, who fulfilled inclusion and exclusion criteria were studied during the year 2016

  • Majority of Discussion 60 patients with facial melasma attended the out patient department of Dermatology, Venereology and Leprosy in the Medical College and Hospital, Mangalore were included in the study

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Summary

Introduction

Melasma is a common hyperpigmentary disorder known for a considerable time. It causes a tremendous emotional and psychosocial distress and plays a major role in affecting the quality of life.[1,2,3]. Glycolic acid is one of the most commonly used and adaptable peeling agent and a member of alpha hydroxy acids It has been found used in a variety of skin disorders including disorders of keratinization like xerosis, icthyosis, commoner skin pigmentary changes like post inflammatory hyperepigmentation, melasma, acne, wrinkles, warts, actinic seborrhoeic keratosis and skin rejuvenation.[26] Glycolic acid can be seen in higher concentrations in chemical peels used in dermatology clinics. This original formula employed a mild steroid dexamethasone 0.1%) in combination with 0.1% tretinoin, and 5% hydroquinone in a cream base

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