A comparative research of venous port access and peripherally inserted central catheter in cancer chemotherapy

Abstract

Objective To analyze the difference of the venous port access (VPA) and peripherally inserted central catheter (PICC) in cancer chemotherapy. Methods All eligible studies on VPA and PICC were searched in the databases of PubMed, China National Knowledge Internet (CNKI), Chinese Biomedical Database (CBM),WANFANG Database and VIP Database. Literatures screening, quality evaluation and data extraction were conducted according to Cochrane Handbook; Meta-analysis was calculated by using RevMan 5.2. Results Twenty-nine studies with a total of 4 449 cases of patients were included in this Meta-analysis, with 1 912 cases in experimental group which adopted VPA and 2 537 cases in controlled group which adopted PICC. Experimental group had advantages in the average catheter retention time (SMD=3.36, 95%CI 2.51-4.21) and quality of life (RR=1.61, 95%CI 1.15-2.24) compared with controlled group. The overall complication rate (RR=0.26, 95%CI 0.20-0.34,P 0.05). Conclusions Compared with PICC, VPA had advantages in a long retention time, fewer complications and few influence on quality of life. Therefore, VPA should be widely used in cancer chemotherapy. Key words: Catheterization, peripheral; Neoplasms; Meta-analysis; Venous port access; Chemotherapy