Abstract
Aim: The aim of this study was to compare and evaluate the effect of four desensitizing agents (Strontium Chloride, Potassium Nitrate, Pro-Argin, Bioactive Glass) on dentinal occlusion. Materials and Methods: Forty freshly extracted mandibular molars were selected. Dentine discs measuring 6x6x3mm were cut off from cervical 1/3rd of molars. The occlusal surface of each dentine disc was abraded with silicon carbide paper for 1 minute and then immersed in 17% Ethylenediaminetetra-acetic acid for 5 minutes. The specimens were then randomly distributed into 4 groups: Strontium Chloride(G1), Potassium Nitrate(G2), Pro-argin (G3) and Bioactive Glass(G4) and brushed with undiluted tooth paste (1 gm) with colgate actibrush 2 minutes daily for 7 days and stored in artificial saliva. Dentine discs were then analyzed by scanning electron microscope. Results: Data were statistically analyzed by one-way Analysis of Variance (ANOVA) and Tukey’s test. The P value for each group was <0.001 showing that highly significant difference existed among the groups. The Bioactive Glass showed maximum amount of dentinal tubule occlusion among all the groups. The least amount of dentinal tubule occlusion was observed in potassium nitrate. The Energy Dispersive X-ray microanalysis showed highest peaks of Calcium and Phosphorous along with presence of Sodium, Magnesium, Potassium, Carbon, Silicon, Oxygen, Phosphorous, Sulphur, Chlorine, and Fluorine. Conclusion: It was concluded that tooth brushing with dentifrice containing bioactive glass showed maximum amount of dentine tubule occlusion. Clinical Relevance: Dentinal hypersensitivity is a significant clinical problem which can cause considerable concern for patients. Appropriate and combine use of various clinically effective both synthetic and natural desensitizing agents may considerably help to manage the problem.
Highlights
Occlusion by forming a glycoprotein on the surface [9]
The least amount of dentinal tubule occlusion was observed in potassium nitrate
Two-way Analysis of Variance (ANOVA) showed that all groups presented a significant tubule occlusion after 7 days for the factor time (P < 0.001)
Summary
Occlusion by forming a glycoprotein on the surface [9]. Bioactive glass is an inorganic amorphousDentinal hypersensitivity is one of the most commonly encountered clinical problems. According to Addy et al dentine hypersensitivity is characterized by “Pain derived from exposed dentine in response to chemical, thermal, tactile, or osmotic stimuli which cannot be explained as arising from any other dental defect or pathology’’[1]. By far the most widely calcium sodium phosphosilicate, originally developed as bone regenerative material. These materials are reactive when exposed to body fluids, and deposit hydroxycarbonate apatite, as a mineral in the enamel and dentine. When incorporated into a dentifrice, particles are deposited onto the dentine surface to mechanically occlude dentinal tubules [10]. The aim of this study was to evaluate and compare the ability of four desensitizing agents – Strontium Chloride, Potassium Nitrate, Pro-Argin and Bioactive Glass on dentinal tubule occlusion using a scanning electron microscope
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