A comparative evaluation of bioresorbable type I collagen membrane with and without fibrin fibronectin sealing system in the treatment of gingival recession: A clinical study

Abstract

Background and Objectives: The purpose of the study was to clinically evaluate and compare the efficacy of type I collagen membrane (BIOMEND REGULAR® ) 1 with and without fibrin fibronectin sealing system (TISSEEL® ) 2 in the treatment of localized gingival recession. Materials and Methods: The study population consisted of 14 patients with a total of 28 gingival recession defects. The selected gingival recession sites were randomly assigned as either experimental site A (BioMend Regular® ) or experimental site B (BioMend Regular® + Tisseel® ). The clinical parameters including plaque index, gingival index, recession depth, recession width, width of keratinized gingiva, probing depth and clinical attachment level were recorded at baseline and at six months and twelve months post-operatively. Results: Twelve months follow-up results showed significant improvements in all clinical parameters for both the treatment groups. The recession width and depth were reduced in both the groups - BioMend Regular® and BioMend Regular® + Tisseel® , with mean root coverage of 31.79% and 35.64%, respectively. Furthermore, the width of keratinized gingiva was increased by 2.71 mm and 3.14 mm for experimental site A and experimental site B respectively when baseline values were compared with twelve month post-operative data. On intergroup comparison, the mean difference in different clinical parameters was statistically not significan. Interpretation and Conclusion: Both groups showed the potential of achieving root coverage; however, on comparison between the two groups, the results obtained of BioMend Regular® with Tisseel® group were slightly better, although statistically not significant.