Abstract
Abstract: Background: Vatarakta can be managed in a number of ways, including with the use of herbs and formulations, as indicated by Ayurvedic texts. However, no systematic data are available on the comparative efficacy of Kokilakshadi Kashayam and Kaishore Guggulu. The purpose of this study is to compare the efficacy of Kaishore Guggulu and Kokilakshadi kashayam in the treatment of Vatarakta patients. Method and design: In a prospective, single-centered, randomized controlled trial, 60 patients, between 19 and 60 years, diagnosed with Vatarakta, presenting with cardinal features of Vatarakta as per Ayurvedic texts, and the Patients having serum uric acid levels of more than 6mg/dl in females & more than 7mg/dl in males will be split into two groups at random. Patients will receive Kaishore Guggulu in one group and Kokilakshadi kashayam in the other. Guidelines regarding Pathya-apathya will be given. 30 days of treatment will be given to each group. Outcomes will be evaluated on the 15th & 30th (During treatment) & 60th day (post-treatment). The primary outcome will be assessed by looking up the Vatarakta cardinal symptoms' grading. Secondary outcomes will check for improvement in laboratory investigations like changes in Serum uric acid levels and the patient's quality of life.
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