A comparative clinicomicrobiological study to evaluate efficacy of superoxide solution with povidone-iodine irrigation in chronic periodontitis patients

Abstract

Introduction: Oxum is a stable, nonflammable, and noncorrosive bactericidal, virucidal, fungicidal, and sporicidal solution that is ready to use with no further dilution or mixing. Superoxidized solutions have shown to be both safe and efficient as a wound care product that moistens, lubricates, debrides, and reduces the microbial load of various types of lesions. Superoxidized solutions are electrochemically processed aqueous solutions manufactured from pure solutions which are rich in reactive oxygen species with neutral pH and longer half-life (>12 months). Aim and Objective: The aim of the present study was to compare superoxide solution with povidone-iodine by means of clinical parameters and microbiologically by colony-forming units. Materials and Methods: A total of 20 sites with chronic periodontitis were selected for study and randomly divided into two groups (ten sites per group). In each patient, sites were selected having probing depth ≥5 mm. The patients were randomly allotted into one of the following groups prior to treatment. Group 1 (study group – irrigation with superoxidized solutions) Group 2 (study group – irrigation with povidone-iodine [Betadine]). The study period of 30 days was divided into baseline (0 day) and 30th day. Periodontal pockets were irrigated with superoxidized solution (oxum) and povidone-iodine (Betadine) from 10 ml syringe having blunt metallic cannula. A total time of 5–10 min was spent for irrigation of the sites. Samples of subgingival plaque from periodontal pockets were obtained with sterile curette at baseline and 1 month for colony-forming units. Results: Group A showed comparable improvement in all the clinical parameters (probing pocket depth and sulcus bleeding index) than Group B. Conclusion: Superoxidized water irrigation as an adjunct to scaling and root planing proved to be effective in the treatment of periodontitis. They allowed better retention and were biologically accepted without any side effects.