Abstract
Background: : Acid peptic disease is the condition in which there is either excessive secretion of acid and pepsin or a weakened stomach mucosal defence, which is responsible for damage to the delicate mucosa and the lining of the stomach, oesophagus and duodenum resulting in ulceration.Parinama shoola in Ayurveda is comparable with Acid peptic disease.Aim of study: The Aim of the study is to evaluate and compare the effect of indigenous compound drugs (Shatavari mandoor and Pippali ghrita) in uncomplicated cases of Parinam shoola.Methods:Â This is a prospective, open labelled, randomised clinical trial. A total of 31 patients suggestive of features of Parinama Shoola (acid peptic disorder) were enrolled and were randomly divided in two groups- 12 patients were enrolled in group A and were given trial drug Shatavari mandoor,19 patients were enrolled in group B and were given trial drug Pippali ghrita. Duration of study was 3 months.Results: Individually both groups showed statistically significant improvement in clinical symptoms i.e. pain in abdomen, epigastric burning, nausea, flatulence, loss of appetite and constipation (p<0.01), but the mean reduction in the symptoms of group A (Shatavari mandoor group) is more than group B (Pippali ghrita group).Conclusion: Both trial drugs are effective in the treatment of Parinama shoola. Shatavari mandoor is more effective in the treatment of Parinam shoola in comparison to Pippali ghrita.Â
Highlights
An ulcer is defined as disruption of mucosal integrity of stomach and or duodenum leading to local defect or excavation due to active inflammation.Peptic ulcers are estimated to occur in 6-15% of general population
This study revealed the effect of herbomineral drugs (Shatavari mandoor & Pippali ghrita ) in the treatment of Parinama shoola
Grouping of patients Patients were randomly divided into two groups Group A: 12 Patients were included in group A and were administered with trial drug Shatavari mandoor
Summary
An ulcer is defined as disruption of mucosal integrity of stomach and or duodenum leading to local defect or excavation due to active inflammation.Peptic ulcers are estimated to occur in 6-15% of general population. Aim of study: The Aim of the study is to evaluate and compar e the effect of indigenous compound dr ugs (Shatavari mandoor and Pippali ghrita) in uncomplicated cases of Parinam shoola. A total of 31 patients suggestive of features of Parinama Shoola (acid peptic disorder) were enrolled and were randomly divided in two groups- 12 patients were enrolled in group A and were given trial drug Shatavari mandoor, patients were enrolled in group B and were given trial drug Pippali ghrita. Results: Individually both gr oups showed statistically significant impr ovement in clinical symptoms i.e. pain in abdomen, epigastric burning, nausea, flatulence, loss of appetite and constipation (p
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
