A Comparative Clinical Study on <i>Agnikarma</i> along with <i>Panchatikta Guggulu</i> in the Management of <i>Janu Sandhigatvata</i> (Osteoarthritis of Knee Joint)

Abstract

Background: Osteoarthritis is characterized by a slow and progressive deterioration of articular cartilage. It is a condition involving the breakdown of the protective cartilage covering the ends of the bones where two bones meet to form a joint. The aim was to evaluate the efficacy of Agnikarma with Panchatikta Guggulu in the management of Janu Sandhigatavata (osteoarthritis of knee joint). A total of 61 patients of Sandhigatavata (osteoarthritis of knee joint) were selected and randomly allocated into two groups, among them 57 were completed and 4 patients dropped out. In group A (n = 29), Agnikarma was done with Panchadhatu Shalaka and Panchatikta Guggulu orally given with lukewarm water after the meal. In group B (n = 28), Agnikarma was done with Panchadhatu Shalaka and a placebo capsule has orally given with lukewarm water after the meal. group‑A provided 70.35% relief in pain while group‑B provided 61.85% relief. Relief from crepitus was observed in 5.55% of patients of group‑A, while 1.92% of patients of group‑B. Both groups provided 68.57% relief in stiffness. There was a statistically insignificant difference between both groups. Group A shows better result in pain relief than group B. Agnikarma with Panchatikta Guggulu is more effective than Agnikarma alone in the management of Janu Sandhigatavata.