Year-end Sale % OFF 
Abstract
The present study aims to highlight the therapeutic potential of Asphodeline lutea (AL), a wild edible plant of the Mediterranean diet. Roots, aerial parts, and flowers of AL at two different phenological stages were collected from three locations in Italy. The inhibitory activities of extracts on strategic enzymes linked to human diseases were assessed. The antioxidant properties were evaluated in vitro, using six standard bioassays. The phenolic and anthraquinone profiles were also established using HPLC-PDA. Zinc, cadmium, lead, and copper contents were also determined. All the samples inhibited acetylcholinesterase (from 1.51 to 2.20 mg GALAEs/g extract), tyrosinase (from 7.50 to 25.3 mg KAEs/g extract), and α-amylase (from 0.37 to 0.51 mmol ACAEs/g extract). Aloe-emodin and physcion were present in all parts, while rhein was not detected. The phenolic profile and the heavy metals composition of specimens gathered from three different regions of Italy were different. It can be argued that samples collected near the street can contain higher concentrations of heavy metals. The experimental data confirm that the A. lutea species could be considered as a potential source of bioactive metabolites, and its consumption could play a positive and safe role in human health maintenance.
Highlights
IntroductionAsphodeline lutea (AL) Reichenb (synonym: Asphodelus luteus L., family Xanthorrhoeaceae), known as King’s Spear or Yellow Asphodel, is a perennial landscaping plant native toSouth-eastern Europe, North Africa and Turkey, characterized by a single stem with semi hollow leaves and yellow-orange flowers [1,2]
Asphodeline lutea (AL) Reichenb, known as King’s Spear or Yellow Asphodel, is a perennial landscaping plant native toSouth-eastern Europe, North Africa and Turkey, characterized by a single stem with semi hollow leaves and yellow-orange flowers [1,2]
We aimed to evaluate the antioxidant activities, the enzyme inhibitory potential of extracts from different anatomical regions of AL, collected in diverse sites in the Italian
Summary
Asphodeline lutea (AL) Reichenb (synonym: Asphodelus luteus L., family Xanthorrhoeaceae), known as King’s Spear or Yellow Asphodel, is a perennial landscaping plant native toSouth-eastern Europe, North Africa and Turkey, characterized by a single stem with semi hollow leaves and yellow-orange flowers [1,2]. The chemotherapeutic value of Bulgarian and Turkish AL root extracts has been evidenced only in recent years, revealing the presence of different therapeutically useful compounds. Molecules 2018, 23, 461 and anti-mutagenic activities of methanol root extracts of AL have been reported [5], while the hepatoprotective and antioxidant capacity of the ethanol root extracts of AL both in vivo and in vitro has been evidenced in an animal model of CCl4 -injured liver [6]. The methanol and chloroform extracts from AL roots caused a marked inhibition of multidrug resistance in mouse tumour cells transfected with the human MDR1 gene [7], whereas methanol, acetone and aqueous extracts of different Asphodeline spp. parts were reported to moderately inhibit elastase, collagenase and hyaluronidase enzymes at 100 μg/mL [8]. Other studies have reported the use of extracts of A. lutea among local populations for skin diseases and haemorrhoids [9,10]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
