Abstract
Abstract Pumpkin seed is being used traditionally for curing and protecting various ailments. The present study was designed to evaluate the anti-inflammatory, anti-oxidant and anti-bacterial activities of ethanol extract of pumpkin (Cucurbita maxima Linn.) seed oil from hybrid and indigenous varieties. An anti-inflammatory, anti-oxidant, and anti-bacterial activities were assessed by BSA (bovine serum albumin) denaturation, in vitro DPPH (2,2-diphenyl-1-picrylhydrazyl) scavenging and disc diffusion methods, respectively. In this study, both varieties of pumpkin seed oil showed remarkable anti-inflammatory and anti-oxidant activities that were in a dose-dependent manner. At a concentration of 45 μg/mL, indigenous pumpkin seed oil (IPSO) showed highly significant (p
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