Abstract
Objective : to assess the effectiveness of tear substitutes in patients suffering from dry eye syndrome (DES). Material and methods . 100 patients with an established diagnosis of mild to moderate DES, averagely aged 42.0 ± 2.1, were divided into three groups: group 1 involving 33 patients (54 eyes, 13 men and 20 women) aged 42.7 ± 2.13 with mild DES, who were treated by low viscosity eye drops, group 2 involving 33 patients (56 eyes, 13 men and 20 women) aged 41.4 ± 2.07 with moderate DES, who were treated by moderate viscosity eye drops and group 3 involving 34 patients (52 eyes, 14 men and 20 women) aged 41.9 ± 2.1 with moderate DES, who were treated by high viscosity eye drops. Treatment results were evaluated after 1 month on the basis of complaints, objective examination data and indicators of the functional tests Results . The complaints (of discomfort, eye strain, fatigue when working with text, eye redness, lacrimation, burning and cramping in the eyes) became less severe, and so did the objective signs of DES. The functional test indicators showed an improvement, too. The best results of the treatment were noted in group 3, where the tear production indicator (Schirmer’s test) increased by 68.1 %. This indicator increased by 66.7 % and 61.5 % in groups 1 and 2, respectively. The LIPCOF test results dropped 3.9 times in group 1 and only 2,3 times in groups 2 and 3. Conclusion . Tear substitutes must be used in DES as the first line of conservative therapy. The improvement of subjective evaluations of the patients and the data of objective research in all three groups is the result of an adequate selection of tear substitutes drugs of a certain degree of viscosity according to the severity of DES.
Highlights
Objective: to assess the effectiveness of tear substitutes in patients suffering from dry eye syndrome (DES)
Material and methods. 100 patients with an established diagnosis of mild to moderate DES, averagely aged 42.0 ± 2.1, were divided into three groups: group 1 involving 33 patients (54 eyes, 13 men and 20 women) aged 42.7 ± 2.13 with mild DES, who were treated by low viscosity eye drops, group 2 involving 33 patients (56 eyes, 13 men and 20 women) aged 41.4 ± 2.07 with moderate DES, who were treated by moderate viscosity eye drops and group 3 involving 34 patients (52 eyes, 14 men and 20 women) aged 41.9 ± 2.1 with moderate DES, who were treated by high viscosity eye drops
Tear substitutes must be used in DES as the first line of conservative therapy
Summary
Tear substitutes must be used in DES as the first line of conservative therapy. The improvement of subjective evaluations of the patients and the data of objective research in all three groups is the result of an adequate selection of tear substitutes drugs of a certain degree of viscosity according to the severity of DES. 2020; 13(1): 7-11 пациентов, имеющих легкую и среднюю степень тяжести клинического течения ССГ, наиболее часто встречающихся в клинической практике, при применении препаратов разной степени вязкости: низкой, средней и высокой. — 1-я группа: 33 человека (54 глаза), в том числе 13 мужчин и 20 женщин, средний возраст — 42,70 ± 2,13 года, с ССГ легкой степени, в лечении которых использовались препараты низкой вязкости;. — 2-я группа: 33 человека (56 глаз), в том числе 13 мужчин и 20 женщин, средний возраст — 41,4 ± 2,07 года, с ССГ средней степени, в лечении которых использовались препараты средней вязкости;. — 3-я группа: 34 человека (52 глаза), в том числе 14 мужчин и 20 женщин, средний возраст — 41,9 ± 2,1 года, с ССГ средней степени тяжести, в лечении которых использовался препарат высокой вязкости. Parameters under evaluation: 1) discomfort and tired eyes; 2) fatigue when working with text; 3) redness of the eyes; 4) tearing; 5) feeling of dryness in the eyes; 6) burning and pain in the eyes; 7) deterioration of visual performance in the evening; 8) itchy eyelids. **p < 0.01 — significance of differences in compared signs between groups before and after treatment; ***p < 0.001 — significance of differences in compared signs between groups before and after treatment
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
