Abstract

Background: Oral squamous cell carcinoma (OSCC) most commonly occurs in the middle-aged and older individuals. It is believed thatrole of aetiologyisdifferent in young and old patients. Objective: This study was conducted to analyse the comparisonof demographic and aetiological difference in young and old patients of buccal mucosa cancer. Materials and Methods: In this retrospective study, demographicand aetiological details were retrieved form medical records between Mar. 2013 and Jan. 2016. Results: The patients were grouped as younger (<40 years) and elder (aged 40 years and above). Of 198 patients, higherincidence was observed in older patients. Both younger and older groups showed male predominance (male: female ratio was 4:1 and 3.7:1 in younger and older groups, respectively). Conclusion: The present study proved that young (<40 yrs) adults with OSCC showed aggressive course compared with elders (≥40 yrs).The aggressiveness of disease may be due to the presence ofrisk habits. However, further studies need to find the hidden risk factors for lower survival.

Highlights

  • Oral squamous cell carcinoma (OSCC) is the leading cause of morbidity and mortality across the world [1]

  • The incidence of oral squamous cell carcinomas varies in different parts of the world and this difference is largely attributed to the exposureto risk factors specific to the area

  • The remaining patients i.e., 11.3% of young and 18.9% of old age groups were diagnosed with poorly differentiated squamous cell carcinoma

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Summary

Introduction

Oral squamous cell carcinoma (OSCC) is the leading cause of morbidity and mortality across the world [1]. The incidence of oral squamous cell carcinomas varies in different parts of the world and this difference is largely attributed to the exposureto risk factors specific to the area. The clinical and epidemiological profile of young and elder population of oral cancer had been reported that higher prevalence and poor prognosis among young patients were associated with male gender, lower educational level and pain symptomatology [7]. Oral squamous cell carcinoma (OSCC) most commonly occurs in the middle-aged and older individuals. Objective: This study was conducted to analyse the comparisonof demographic and aetiological difference in young and old patients of buccal mucosa cancer. Conclusion: The present study proved that young (

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