Abstract
Results The total number of reported ADRs increased from 420 to 1265. The most common ADR reporters were doctors (59.4%), followed by nurses (29.4%) which was significantly increased from 2012 (8.8%). The most common causative drugs were antibiotics (30.6%), followed by miscellaneous drugs (30.4%), and antituberculosis drugs (10%), and clinical manifestations of ADRs were cutaneous (41.9%), gastrointestinal (24.9%) and neurophsychiatric symptoms (18.5). The distribution of causative drugs and clinical manifestations were differed from those in 2012. Majority of the health care workers reported ADR reporting is necessary (98.9%) and is their obligation (96.3%), while only 38.1% have reported ADR. Conclusions The number of reported ADRs significantly increased since the introduction of RPVC in a tertiary hospital. The causative drugs and clinical manifestations of ADRs changed. The ADR reporters diversified and they have the knowledge and responsibility to ADR reporting.
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